Pulcaris Ltd is an Israeli Startup company that is active in the Health & Beauty sector. 
Yisrael Kezra, together with a team of highly experienced Academics from the Hebrew University, has conducted intensive research into indigenious plants from the Negev desert.
The company has now isolated a very promising ingredient that is extracted from desert plants, which will be used in the cosmetic and derma cosmetic markets. Excellent results have been achieved in clinical tests.
The...Read more

Pulcaris Ltd is an Israeli Startup company that is active in the Health & Beauty sector. 

Yisrael Kezra, together with a team of highly experienced Academics from the Hebrew University, has conducted intensive research into indigenious plants from the Negev desert.

The company has now isolated a very promising ingredient that is extracted from desert plants, which will be used in the cosmetic and derma cosmetic markets. Excellent results have been achieved in clinical tests.

The ingredient and production process are patented.

Findings

The beneficial activity of Pi212 observed in our studies is a combination of its anti-inflammatory and antioxidant activity. Our researched showed that Pi212 prevented 89% of skin oxidative stress (ROS). Immune cell infiltration of atopic dermatitis is characterized by the release of (ROS)reactive oxygen species H2O2. Subcutaneous administration of Pi212 to skin oxazolone treated mice caused a marked reduction (99%) in the induced activity. Our findings suggest that Pi212 is a potential agent for the treatment of skin disease such as atopic dermatitis and psoriasis, it can also be used to help repair skin from sun damage and environmental toxicity.